DIM Avail 100 mg 120 Softgels

Research tells us that a low level of the 2-hydroxyestrone and a high level of 16 alpha-hydroxyestrone is associated with an enhanced risk of breast cancer. DIM increases 2-hydroxyestrone and therefore improves the 2/16 hydroxyestrone ratio, making it very protective for women and men at high risk for this condition. Research by Bradlow has shown that DIM also reduces availability of 4-androstenedione for aromatization to estrone, a more dangerous form of estrogen. He concludes that DIM is more potent than I3C at protecting against breast cancer due to decreased formation of 16 alpha-hydroxyestrone from estrone. DIM supplementation improves the estrogen ratio in a favorable direction that protects both men and women without the negative effect of raising 4 hydroxyestrogen as seen with I3C. DIM does not block ovulation the way I3C does, and can be used safely along with Tamoxifen, unlike I3C.